Cayman Chemical OrexIn B amIdehumntrIfl 500ug
A hypothalamic neuropeptide; an OX receptor agonist (IC50s = 420 and 36 nM, respectively, for human OX1 and OX2 receptors); induces transient increases in intracellular calcium in CHO cells stably expressing OX1 and OX2 (EC50s = 2,500 and 60 nM, respectively) and in primary rat VTA dopaminergic neurons; stimulates arachidonic acid release from CHO cells expressing human recombinant OX1 (EC50 = 4.17 nM); stimulates food intake in freely feeding mice (30 nmol, i.c.v.); stimulates food intake in goldfish (10 ng/g, i.c.v.)